Run to Fallout 4 on computers with 4GB of RAM.
Fallout 4 requires more 4GB of RAM, but the players did a patch which will start Fallout 4 to 4GB of RAM.
Setting: Set the folder with Fallout 4.
Download: Fallout 4 patch 4GB RAM
P.S. it is worth noting that the levels will load a little bit longer than usual.